Let’s Rethink Diabesity: Semaglutide Dosing and Titration

Identify patients who may benefit from semaglutide and recognise important contraindications and precautions.

Complete a focused baseline assessment before initiating therapy.

Apply indication-appropriate initiation, dose-escalation and maintenance schedules.

Counsel patients on injection technique, missed doses, realistic expectations, nutrition, hydration and physical activity.

Manage common gastrointestinal adverse effects and determine when dose escalation should be delayed, treatment held or urgent assessment arranged.

Reduce hypoglycaemia risk by reviewing sulfonylurea and insulin therapy when semaglutide is introduced.

Use cardiometabolic, renal, hepatic, tolerability and access considerations to individualise treatment.

Learning Objectives